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Image in Cardiology
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Disponível online em 6 de janeiro de 2026

Turning the heart around: Pacemaker implantation in situs inversus

Implantação de pacemaker num doente com situs inversus: um desafio anatómico
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Joana Certo Pereiraa,
Autor para correspondência
joanacerto@gmail.com

Corresponding author.
, Isabel Santosa, Francisco Gamaa,b, Pedro Adragãoa,b
a Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal
b Department of Cardiology, Hospital da Luz, Lisbon, Portugal
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Case presentation

We present the case of a 79-year-old man with situs inversus totalis who was admitted to the emergency department for syncope caused by high-grade atrioventricular block, with no identifiable reversible causes. Transthoracic echocardiography revealed preserved ejection fraction and no valvular disease.

The chest X-ray showed situs inversus, leading to a thoracic computed tomography scan to confirm the venous anatomy. The computed tomography scan confirmed the complete mirror-image anatomy and excluded venous drainage abnormalities (Figure 1A and B). Despite the unusual anatomy, a dual-chamber pacemaker was successfully implanted in the left prepectoral region via ultrasound-guided axillary vein puncture. Atrial and ventricular leads were positioned in the right atrial appendage and right ventricular apex, respectively (Figure 1E and F), with appropriate electrical parameters.

Figure 1.

Dual-chamber pacemaker implantation in a patient with situs inversus totalis with dextrocardia. (A) Axial view and (B) coronal view of thoracic computed tomography scan showing mirror-image anatomy with dextrocardia, normal atrioventricular and ventriculoarterial connections, and right-sided liver. (C) Baseline ECG showing sinus rhythm with right bundle branch block and left posterior fascicular block. (D) ECG performed after syncope revealing trifascicular block with second-degree atrioventricular block Mobitz type II. (E) Posteroanterior and (F) lateral chest radiographs demonstrating left-sided pacemaker generator with transvenous leads directed toward the right atrial appendage and right ventricular apex, confirming successful pacemaker implantation. LA: left atrium; LV: left ventricle; RA: right atrium; RV: right ventricle; PA: pulmonary artery.

This case illustrates the importance of pre-procedural imaging in patients with situs inversus and demonstrates that standard transvenous pacemaker implantation is feasible with careful planning, despite the anatomical inversion.

Funding

None declared.

Conflict of interest

None declared.

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