Original InvestigationPrognostic Value of Fractional Flow Reserve: Linking Physiologic Severity to Clinical Outcomes
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Dr. Johnson has received internal funding from the Weatherhead PET Center for Preventing and Reversing Atherosclerosis; signed nonfinancial, nondisclosure agreements with St. Jude Medical and Volcano Corporation to discuss coronary physiology projects; and received significant institutional research support from both companies. Drs. Lai and Zhu have received internal funding from the Weatherhead PET Center for Preventing and Reversing Atherosclerosis. Dr. Barbato has received institutional consultancy fees and research support from St. Jude Medical. Dr. Hamilos has received consulting fees from St. Jude Medical. Dr. Jensen has received grant support from St Jude Medical, Terumo, and Biosensors. Dr. Koo has received institutional research support from St. Jude Medical. Dr. Palop has received research grants from Abbott Vascular, Terumo; and Medtronic; and honoraria for advisory panels and presentations from Medtronic, Abbott Vascular, Boston Scientific, Terumo, Volcano, St. Jude, Eli Lilly and AstraZeneca. Dr. Muller has received research support from the Fondation Vaudoise de Cardiologie, Lausanne, Switzerland; and has received honoraria for presentations from St. Jude Medical and Medtronic. Dr. Van Belle has served as a consultant for St. Jude Medical and received speaker's fees and honoraria from Volcano and St. Jude Medical. Dr. Fearon has received research support from St. Jude Medical and Medtronic; speaker’s fees from Medtronic; and owns minor stock options in HeartFlow Inc. Dr. Pijls has served as a consultant to St. Jude Medical and HeartFlow Inc; and has received institutional grant support from St. Jude Medical. Dr. De Bruyne has received consulting fees and research support from St. Jude Medical; his consulting fees are passed to Cardiovascular Research Center Aalst, a not-for-profit organization. Dr. Gould has received internal funding from the Weatherhead PET Center for Preventing and Reversing Atherosclerosis; signed nonfinancial, nondisclosure agreements with St. Jude Medical and Volcano Corporation to discuss coronary physiology projects; 510(k) applicant for cfrQuant, a software package for quantifying absolute flow using cardiac positron emission tomography, and all royalties will go to a University of Texas scholarship fund, as the University of Texas has a commercial, nonexclusive agreement with Positron Corporation to distribute and market cfrQuant in exchange for royalties, but Dr. Gould retains the ability to distribute cost-free versions to selected collaborators for research. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.