TY - JOUR T1 - Incidence and predictors of vascular access site complications following transfemoral transcatheter aortic valve implantation JO - Revista Portuguesa de Cardiologia (English edition) T2 - AU - Fonseca,Paulo AU - Almeida,João AU - Bettencourt,Nuno AU - Ferreira,Nuno AU - Carvalho,Mónica AU - Ferreira,Wilson AU - Caeiro,Daniel AU - Gonçalves,Helena AU - Ribeiro,José AU - Rodrigues,Alberto AU - Braga,Pedro AU - Gama,Vasco SN - 21742049 M3 - 10.1016/j.repce.2015.11.041 DO - 10.1016/j.repce.2015.11.041 UR - https://www.revportcardiol.org/en-incidence-predictors-vascular-access-site-articulo-S2174204917302866 AB - Introduction and ObjectivesVascular access site complications in transfemoral (TF) transcatheter aortic valve implantation (TAVI) are associated with increased morbidity and mortality; however, their incidence and predictors are conflicting between studies. This study sought to assess the incidence and predictors of vascular access site complications in patients undergoing TF TAVI. MethodsA total of 140 patients undergoing TF TAVI were included in the study. Minimum iliofemoral diameter and iliofemoral calcium score (CS) were estimated from contrast-enhanced multidetector computed tomography imaging, using different thresholds according to aortic luminal attenuation. To assess the impact of the learning effect, the first 50% of TF TAVI procedures were compared to the remainder. ResultsFifty-one patients presented access site complications (7.1% major, 29.3% minor), most of which were local bleeding or hematoma (11.4%), pseudoaneurysm (7.9%) or closure device failure (5.0%). In a multivariate logistic regression analysis that included sheath-to-iliofemoral artery ratio (SIFAR) (the ratio between the sheath outer diameter and minimum iliofemoral diameter), iliofemoral CS and center experience, SIFAR was the sole independent predictor of access site complications (hazard ratio 14.5, confidence interval [CI] 95% 1.75–120.12, p=0.013). The SIFAR threshold with the highest sum of sensitivity (71.4%) and specificity (53.4%) for access site complications was 0.92 (area under the curve 0.66, 95% CI 0.56–0.75, p=0.002). ConclusionsVascular access site complications are frequent in patients undergoing TF TAVI. SIFAR was the only independent predictor of access site complications and therefore should be systematically assessed during pre-procedural imaging study. ER -