TY - JOUR T1 - The prognostic value of admission red cell distribution width-to-platelet ratio in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention JO - Revista Portuguesa de Cardiologia (English edition) T2 - AU - Pusuroglu,Hamdi AU - Cakmak,Huseyin Altug AU - Akgul,Ozgur AU - Erturk,Mehmet AU - Surgit,Ozgur AU - Akkaya,Emre AU - Bulut,Umit AU - Yildirim,Aydin SN - 21742049 M3 - 10.1016/j.repce.2015.10.005 DO - 10.1016/j.repce.2015.10.005 UR - https://www.revportcardiol.org/en-the-prognostic-value-admission-red-articulo-S2174204915002184 AB - ObjectiveRed cell distribution width (RDW) is a measure of variation in the size of circulating red blood cells. Recent studies have reported a strong independent relation between elevated RDW and short- and long-term prognosis in various disorders.The aim of the present study was to investigate the relationship between admission RDW-to-platelet ratio (RPR) and in-hospital and long-term prognosis in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). MethodsA total of 470 consecutive patients with a diagnosis of STEMI who underwent primary PCI were included in this prospective study. The patients were divided into two groups based on their admission RPR: high (>0.061) RPR group and low (≤0.061) RPR group. The patients were followed for adverse clinical outcomes in-hospital and for up to one year after discharge. ResultsIn-hospital cardiovascular mortality, major adverse cardiovascular events (MACE), advanced heart failure and cardiogenic shock were significantly higher in the high RPR group (p<0.05). All-cause and cardiovascular mortality, MACE, fatal reinfarction, advanced heart failure, and rehospitalization for cardiac cause were more frequent in the high RPR group in one-year follow-up (p<0.05). High RPR was found to be a significant independent predictor of one-year cardiovascular mortality in multivariate analysis (p=0.003, OR: 3.106, 95% CI: 1.456–6.623). ConclusionRPR is an inexpensive and readily available biomarker that provides an additional level of risk stratification beyond that provided by conventional risk parameters in predicting long-term MACE and cardiovascular mortality in STEMI. ER -